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Saturday, May 2, 2020 | History

5 edition of Sodium metabolism in disease found in the catalog.

Sodium metabolism in disease

by John Douglas Swales

  • 388 Want to read
  • 1 Currently reading

Published by Lloyd-Luke in London .
Written in English

    Subjects:
  • Sodium -- Metabolism -- Disorders,
  • Hypertension

  • Edition Notes

    Statement[by] J. D. Swales.
    Classifications
    LC ClassificationsRC632.S6 S9
    The Physical Object
    Paginationxi, 324 p. :
    Number of Pages324
    ID Numbers
    Open LibraryOL4851128M
    ISBN 100853241163
    LC Control Number75596386

    A R T I C L E Salt, energy, metabolic rate, and longevity. In the s, when the pharmaceutical industry was beginning to promote some new chemicals as diuretics to replace the traditional mercury compounds, Walter Kempner’s low-salt “rice diet” began to be discussed in .   Data are discussed which demonstrate that insulin plays an important role in sodium metabolism. The primary action of insulin on sodium balance is exerted on the kidney. Increases in plasma insulin concentration within the physiological range stimulate sodium reabsorption by the distal nephron segments and this effect is independent of changes in circulating metabolites or other Cited by:

    Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. The Metabolism, Diet and Disease conference aims to show how basic research on the biochemistry, cell biology and genetics of metabolism can address the major health problems of cancer, obesity, diabetes and insulin resistance, and can explain ageing and longevity.

    This section is from the book "Chemistry Of Food And Nutrition", by Henry C. Sherman. Also available from Amazon: Chemistry of food and nutrition. The distribution of sodium and potassium in the body and some of their mutual relations in metabolism have been referred to in the section on the chlorides. Metabolic Disease of the Newborn and Young Child: Inborn. Errors of Metabolism. Chapter Outline. 1. Describe the epidemiology, clinical features, and emergency management of diabetes mellitus (DM), adrenal insufficiency, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), water intoxication, and diabetes insipidus (DI). 2.


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Sodium metabolism in disease by John Douglas Swales Download PDF EPUB FB2

Reptilian sodium and potassium metabolism involves an active renin–angiotensin system with direct action on osmoregulation.

Some reptiles have nasal salt glands that participate in the regulation of sodium, potassium, and chloride concentrations in the blood. Therefore disorders of the salt gland may affect the electrolyte balance.

Additional Physical Format: Online version: Swales, J.D. (John Douglas). Sodium metabolism in disease. London: Lloyd-Luke, (OCoLC) Online version. The KDIGO (Kidney Disease: Improving Global Outcomes) Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease recommends lowering sodium intake to Cited by: 1.

Sodium is a chemical element with the symbol Na (from Latin natrium) and atomic number It is a soft, silvery-white, highly reactive is an alkali metal, being in group 1 of the periodic table, because it has a single electron in its outer shell, which it readily donates, creating a positively charged ion—the Na + only stable isotope is 23 : group 1: H and alkali metals.

Sodium metabolism in health and disease. Oxford, Blackwell Scientific Publications [] (OCoLC) Online version: Black, Douglas, Sir. Sodium metabolism in health and disease. Oxford, Blackwell Scientific Publications [] (OCoLC) Document Type: Book: All Authors / Contributors: Douglas Black, Sir.

Sodium functions in the body to regulate nerve impulses, balance fluids, and contract and relax muscles. The typical American diet contains twice the amount of sodium a person needs, and too much sodium puts you at increased risk for high blood pressure and heart disease.

NORMAL SODIUM METABOLISM Sodium intake - normal typical western diet consists of mmol – of sodium chloride daily. Absorption of sodium from intestine is via two mechanisms first by being freely permeable across the interstitial cell and secondly by symport with glucose and aminoacids.

Sodium excretion - the regulation of sodium excretion. Sodium Metabolism Disorders Caused when our sodium levels are too high or too low, sodium metabolic disorders can lead to muscle weakness, vomiting and excessive sweating.

An electrolyte, sodium is an essential mineral that helps our muscles and nerves work. Sodium metabolism in health and disease [Douglas Black] on *FREE* shipping on qualifying offers.

Sodium distribution in species Humans. The minimum physiological requirement for sodium is between and milligrams per day depending on sweating due to physical activity, and whether the person is adapted to the climate.

Sodium chloride is the principal source of sodium in the diet, and is used as seasoning and preservative, such as for pickling and jerky; most of it comes from. Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF.

Visit to get more information about this book, to buy it in print, or to download it as a free PDF. Sodium Metabolism in Health and Disease Hardcover – January 1, by Douglas Black (Author) See all formats and editions Hide other formats and editions. Price Author: Douglas Black. Sodium - Metabolism Digestive absorption.

Sodium intake from food, primarily in the form of chloride, is 1 to 4 g per day. The digestive absorption of sodium is very fast and almost complete. Tissue distribution In blood. Almost the total amount of sodium in blood is in the plasma, there is very little in blood cells.

Water and sodium balance are closely interdependent. Total body water (TBW) is about 60% of body weight in men (ranging from about 50% in obese people to 70% in lean people) and about 50% in women. Almost two thirds of TBW is in the intracellular compartment (intracellular fluid, or ICF); the other one third is extracellular (extracellular.

T1 - Sodium Metabolism in Chronic Kidney Disease. AU - Paller, Mark S. PY - /1/1. Y1 - /1/1. N2 - Sodium balance is reasonably well maintained in CKD until renal function is seriously diminished.

CKD patients do not usually develop either edema or sodium by: 1. Therefore, the control of sodium excretion is an interplay between the factors determining glomerular filtration and those determining Funding and Disclosures.

Most of the body’s sodium is located in blood and in the fluid around cells. Sodium helps the body keep fluids in a normal balance (see About Body Water). Sodium plays a key role in normal nerve and muscle function.

The body obtains sodium through food and drink and loses it primarily in sweat and urine. Healthy kidneys maintain a consistent. Sodium metabolism. Barratt LJ. This brief review attempts to summarize important basic concepts of sodium metabolism including sodium ion distribution, sodium balance and the renal regulation of sodium excretion.

Finally, an attempt has been made to relate these basic concepts to the mechanisms and management of common clinical situations of.

Hyponatremia (low sodium) and hypernatremia (high sodium) are the two main classifications of sodium metabolism disorders. Sodium is responsible for helping to maintain the fluid balance of the body, and sodium concentrations are regulated by the kidneys and certain hormones.

When the body's sodium balance is disrupted, telltale symptoms appear. In chronic renal disease when acidosis ex­ists, sodium depletion occurs due to poor tubular reabsorption of sodium as well as to the loss of sodium in the buffering of acids. iii. In case, a person is not adapted to a high environmental temperature, large amount of sodium is lost in the sweat due to ex­treme sweating developing muscular.

Chronic Renal Disease comprehensively investigates the physiology, pathophysiology, treatment, and management of chronic kidney disease (CKD).This translational reference takes an in-depth look at CKD while excluding coverage of dialysis or transplantation, which are both well detailed in other textbooks and Edition: 1.

Sodium Bicarbonate Therapy in Patients with Chronic Kidney Disease Long-lasting therapy with sodium bicarbonate is extensively used for management of metabolic acidosis associated with chronic kidney disease (CKD), as current guidelines suggest sodium bicarbonate supplementation to maintain serum bicarbonate ≥ 22 mmol/L (mM) (level of Cited by: Levothyroxine has a narrow therapeutic index.

Avoid undertreatment or overtreatment, which may result in adverse effects on growth and development in pediatric patients, cardiovascular function, bone metabolism, reproductive function, cognitive function, emotional state, GI function, and glucose and lipid metabolism.

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